Episode 54

Papers Unplugged: TIF Guidelines for the Management of Patients with Transfusion-Dependent Thalassemia (TDT)

What are the latest guidelines for the management of patients with Transfusion-Dependent Thalassemia (TDT)?


In 2022, the fourth edition of the TIF (Thalassemia International Federation) guidelines for the management of patients with transfusion-dependent thalassemia (TDT) was published.

In this podcast, Prof Ali Taher discusses with our host, Dr Nathalie van Havre, the main news of this edition, including genetic work-up, chelation therapy, and prevention and management of complications.

Furthermore, Prof Taher illustrates the innovative gene therapy approaches and new drugs (such as luspatercept, the most recently approved drug for TDT) currently available for the treatment of these patients and how they can impact the management of TDT.

The podcast is based on the paper "2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia", by Farmakis D et al., published in HemaSphere in 2022 (HemaSphere. 2022;6:e732).

Host: Dr Nathalie van Havre; Guest: Prof Ali Taher


This is the sixth of a series of podcasts discussing recently published scientific articles. More podcasts will be available in the future. Stay tuned!


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European Hematology Association

The European Hematology Association promotes excellence in patient care, research, and education in hematology. We serve medical professionals, researchers, and scientists with an active interest in hematology. We are proud to be the largest European-based organization connecting hematologists worldwide to support career development and research, harmonize hematology education, and advocate for hematologists and hematology